PAK3 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
12 results for "PAK3" in Products
12 results for "PAK3" in Products
PAK3 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
| Reactivity: | Human, Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human, Mouse, Monkey |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1H7 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: PAK3 Antibody (1H7) [H00005063-M07]](https://resources.bio-techne.com/images/products/PAK3-Antibody-1H7-Western-Blot-H00005063-M07-img0004.jpg "Western Blot: PAK3 Antibody (1H7) [H00005063-M07]")
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #4G8F11 |
| Applications: | WB, ELISA |
![Western Blot: PAK3 Antibody (4G8F11)BSA Free [NBP2-61766]](https://resources.bio-techne.com/images/products/PAK3-Antibody-4G8F11-Western-Blot-NBP2-61766-img0003.jpg "Western Blot: PAK3 Antibody (4G8F11)BSA Free [NBP2-61766]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PAK3 Antibody [NBP2-19682]](https://resources.bio-techne.com/images/products/PAK3-Antibody-Western-Blot-NBP2-19682-img0004.jpg "Western Blot: PAK3 Antibody [NBP2-19682]")
Recombinant Monoclonal Antibody
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #0K1I5 |
| Applications: | IHC, WB |
![Western Blot: PAK3 Antibody (0K1I5) [NBP3-16173]](https://resources.bio-techne.com/images/products/PAK3-Antibody-0K1I5-Western-Blot-NBP3-16173-img0003.jpg "Western Blot: PAK3 Antibody (0K1I5) [NBP3-16173]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #4G8A5 |
| Applications: | WB, ELISA |
![Western Blot: PAK3 Antibody (4G8A5)BSA Free [NBP2-61767]](https://resources.bio-techne.com/images/products/PAK3-Antibody-4G8A5-Western-Blot-NBP2-61767-img0003.jpg "Western Blot: PAK3 Antibody (4G8A5)BSA Free [NBP2-61767]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3A12 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: PAK3 Antibody (3A12) [H00005063-M08]](https://resources.bio-techne.com/images/products/PAK3-Antibody-3A12-Western-Blot-H00005063-M08-img0004.jpg "Western Blot: PAK3 Antibody (3A12) [H00005063-M08]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PAK3 Antibody [NBP2-38890]](https://resources.bio-techne.com/images/products/PAK3-Antibody-Western-Blot-NBP2-38890-img0002.jpg "Western Blot: PAK3 Antibody [NBP2-38890]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Potent PAK inhibitor; brain penetrant and orally bioavailable
| Chemical Name: | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
| Purity: | ≥98% (HPLC) |
