PDK-1 Products
PDK-1 (Phosphoinositide-dependent Kinase-1), also called PKB kinase and PDPK1, is a member of the AGC group of serine/threonine kinases. Following insulin, growth factor, or pervanadate stimulation, PDK-1 phosphorylates and activates kinases from the Akt, p70 S6K, and RSK families, and is therefore involved in the regulation of cell proliferation and apoptosis.
20 results for "PDK-1" in Products
20 results for "PDK-1" in Products
PDK-1 Products
PDK-1 (Phosphoinositide-dependent Kinase-1), also called PKB kinase and PDPK1, is a member of the AGC group of serine/threonine kinases. Following insulin, growth factor, or pervanadate stimulation, PDK-1 phosphorylates and activates kinases from the Akt, p70 S6K, and RSK families, and is therefore involved in the regulation of cell proliferation and apoptosis.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #650308 |
| Applications: | WB, Simple Western, ICC |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_002613 |
| Applications: | BA |
PDPK1 (PDK1) inhibitor
| Chemical Name: | N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Highly potent, selective PDPK1 (PDK1) inhibitor
| Chemical Name: | (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide |
| Purity: | ≥98% (HPLC) |
PDPK1 (PDK1) inhibitor; inhibits Akt signaling
| Chemical Name: | 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide |
| Purity: | ≥98% (HPLC) |
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
| Chemical Name: | α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Purity: | ≥98% |
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3/4 inhibitor
| Chemical Name: | N-[4-(2-Chloro-5-methyl-4-pyrimidinyl)phenyl]-N-[[4-[[(2,2-difluoroacetyl)amino]methyl]phenyl]methyl]-2,4-dihydroxybenzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![PDK-1 [p Tyr9] Antibody](https://resources.bio-techne.com/images/products/nbp3-23292_rabbit-pdk-1-p-tyr9-pab-19920231992816.jpg "Western Blot: PDK-1 [p Tyr9] Antibody [NBP3-23292] -")
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor
| Chemical Name: | Bis(morpholinothiocarbonyl) disulfide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #M146 |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Applications: | WB |
![Western Blot: PDK-1 Overexpression Lysate [NBL1-14259]](https://resources.bio-techne.com/images/products/PDPK1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14259-img0002.jpg "Western Blot: PDK-1 Overexpression Lysate [NBL1-14259]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![PDK-1 Antibody Western Blot: PDK-1 Antibody [NBP3-25044]](https://resources.bio-techne.com/images/products/nbp3-25044_rabbit-pdk-1-pab-2012202314593090.jpg "Western Blot: PDK-1 Antibody [NBP3-25044]")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2E2 |
| Applications: | WB, ELISA |
![Western Blot: PDK-1 Antibody (2E2) [H00005170-M05]](https://resources.bio-techne.com/images/products/PDK-1-Antibody-2E2-Western-Blot-H00005170-M05-img0002.jpg "Western Blot: PDK-1 Antibody (2E2) [H00005170-M05]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: PDK-1 Antibody [NBP2-44132]](https://resources.bio-techne.com/images/products/PDPK1-Antibody-Western-Blot-NBP2-44132-img0001.jpg "Western Blot: PDK-1 Antibody [NBP2-44132]")
| Applications: | WB |
![Western Blot: PDK-1 Overexpression Lysate [NBL1-14260]](https://resources.bio-techne.com/images/products/PDPK1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14260-img0002.jpg "Western Blot: PDK-1 Overexpression Lysate [NBL1-14260]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: PDK-1 Antibody [NBP2-48631]](https://resources.bio-techne.com/images/products/PDPK1-Antibody-Immunohistochemistry-Paraffin-NBP2-48631-img0002.jpg "Immunohistochemistry-Paraffin: PDK-1 Antibody [NBP2-48631]")
| Applications: | AC |