TIM-1/KIM-1/HAVCR: Proteins and Enzymes
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
12 results for "TIM-1/KIM-1/HAVCR Proteins and Enzymes" in Products
12 results for "TIM-1/KIM-1/HAVCR Proteins and Enzymes" in Products
TIM-1/KIM-1/HAVCR: Proteins and Enzymes
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
This protein is in the process of being discontinued.
| Source: | NS0 |
| Accession #: | AAC39862 |
| Applications: | BA |
Biotinylated
| Source: | HEK293 |
| Accession #: | AAC39862.1 |
| Applications: | BA, BA, Bind |
| Source: | NS0 |
| Accession #: | NP_599009.2 |
| Applications: | BA, BA |
| Applications: | AC |
(268 aa)
| Source: | HEK293 |
| Accession #: | AAC39862 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | NP_599009.2 |
| Applications: | BA, BA |
| Source: | NS0 |
| Accession #: | O54947 |
| Applications: | BA |
| Applications: | AC |
| Source: | HEK293 |
| Accession #: | Q96D42.3 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | BAJ61042 |
| Applications: | BA |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human TIM-1/KIM-1/HAVCR His Protein [NBP2-52037]](https://resources.bio-techne.com/images/products/TIM-1-KIM-1-HAVCR-Recombinant-Protein-SDS-Page-NBP2-52037-img0001.jpg "SDS-PAGE: Recombinant Human TIM-1/KIM-1/HAVCR His Protein [NBP2-52037]")