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TSC2 Products

TSC2, also called tuberin, complexes with TSC1 (hamartin) to inhibit cell proliferation by antagonizing mTOR/p70S6K signaling. Its location either in the cytoplasm or the nucleus is regulated by phosphorylation and the cell cycle. Numerous point mutations are associated with development of tumors (hamartomas) in kidney, heart, skin and brain. Human TSC2 shares 91% amino acid (aa) identity with mouse TSC2 over aa 550-850. Splice variants that are missing aa 946 to 988 or 989 may show different tissue distribution than full length TSC2.

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106 results for "TSC2" in Products

106 results for "TSC2" in Products

TSC2 Products

TSC2, also called tuberin, complexes with TSC1 (hamartin) to inhibit cell proliferation by antagonizing mTOR/p70S6K signaling. Its location either in the cytoplasm or the nucleus is regulated by phosphorylation and the cell cycle. Numerous point mutations are associated with development of tumors (hamartomas) in kidney, heart, skin and brain. Human TSC2 shares 91% amino acid (aa) identity with mouse TSC2 over aa 550-850. Splice variants that are missing aa 946 to 988 or 989 may show different tissue distribution than full length TSC2.

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Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody.

Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB, IP
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, ELISA, MA, AP
Applications: WB, ELISA
Reactivity: Human
Applications: AC
Applications: IP, WB (-)
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: AC
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