UBIAD1: Proteins and Enzymes

UBIAD1 is a novel gene designated TERE1 that has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified, in loss of heterozygosity studies, as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation, and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer.