VAV3 Products
The Vav family are Rho/Rac guanosine nucleotide exchange factors (GEFs), consisting of three members in mammalian cells (Vav, Vav2, Vav3) and one in nematodes (CelVav) (1). Vav3 is expressed in most hematopoietic cells and non-hematopoietic tissues except ovary and skeletal muscles. T-cell stimulated and tyrosine phosphorylated Vav3 acts as an exchange factor for GTP-binding proteins RhoA, RhoG, and Rac1 (2). Also, tyrosine phosphorylated Vav3 mediates RTK signalizing, specifically IR, IGFR, and EGFR-mediated signaling pathways. Vav3 has been linked to as a factor for cell morphology modulation and an inducer for cell transformation (3).
Show More
9 results for "VAV3" in Products
9 results for "VAV3" in Products
VAV3 Products
The Vav family are Rho/Rac guanosine nucleotide exchange factors (GEFs), consisting of three members in mammalian cells (Vav, Vav2, Vav3) and one in nematodes (CelVav) (1). Vav3 is expressed in most hematopoietic cells and non-hematopoietic tissues except ovary and skeletal muscles. T-cell stimulated and tyrosine phosphorylated Vav3 acts as an exchange factor for GTP-binding proteins RhoA, RhoG, and Rac1 (2). Also, tyrosine phosphorylated Vav3 mediates RTK signalizing, specifically IR, IGFR, and EGFR-mediated signaling pathways. Vav3 has been linked to as a factor for cell morphology modulation and an inducer for cell transformation (3).
Show More
Applications: WB, ICC/IF, Flow, IP
Reactivity:
Human,
Mouse
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #SR2314 |
Applications: | WB, ICC/IF, Flow, IP |
Applications: IHC, ELISA, ICC/IF, Flow
Reactivity:
Human
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | IHC, ELISA, ICC/IF, Flow |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #9A10D8 |
Applications: | IHC, WB |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit Polyclonal |
Applications: | WB |
Applications: | WB |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |