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VHR Products

Vaccinia Virus VH1-related Phosphatase (VHR), also known as Dual-Specificity Phosphatase 3 (DUSP3), removes phosphate groups from tyrosine, serine, and threonine residues. It belongs to a family of phosphatases that selectively dephosphorylate MAP kinases. VHR has been shown to act as a phosphatase on several members of the MAP kinase family, including ERK1, ERK2, and JNK. It is a target for the ZAP-70 kinase, and phosphorylation of VHR at tyrosine 138 leads to a downregulation of ERK2 activity. Its well-defined biochemistry has made VHR useful in screening assays for compounds that inhibit phosphatases.

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61 results for "VHR" in Products

61 results for "VHR" in Products

VHR Products

Vaccinia Virus VH1-related Phosphatase (VHR), also known as Dual-Specificity Phosphatase 3 (DUSP3), removes phosphate groups from tyrosine, serine, and threonine residues. It belongs to a family of phosphatases that selectively dephosphorylate MAP kinases. VHR has been shown to act as a phosphatase on several members of the MAP kinase family, including ERK1, ERK2, and JNK. It is a target for the ZAP-70 kinase, and phosphorylation of VHR at tyrosine 138 leads to a downregulation of ERK2 activity. Its well-defined biochemistry has made VHR useful in screening assays for compounds that inhibit phosphatases.

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Applications: WB
Reactivity: Human, Mouse, Rat
Applications: IHC
Reactivity: Human
Applications: EnzAct
Applications: WB, ELISA, IP
Reactivity: Human
Applications: IHC, WB
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human
Applications: IHC, WB, ICC/IF
Reactivity: Human
Applications: AC
Applications: ICC/IF
Reactivity: Human
Applications: WB
Applications: ELISA
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, ELISA, IP
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
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