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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry

Label

mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 393314

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human Claudin-12
Met1-Thr244
Accession # NP_036261

Specificity

Detects human Claudin-12. Stains human Claudin-12 transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Claudin-12 Antibody (393314) [mFluor Violet 450 SE]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Claudin-12

Claudins, such as CLDN12, are components of epithelial cell tight junctions. Tight junctions regulate movement ofsolutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of theapical and basolateral plasma membrane domains (Acharya et al., 2004).(supplied by OMIM)

Alternate Names

Claudin12, CLDN12

Gene Symbol

CLDN12

Additional Claudin-12 Products

Product Documents for Claudin-12 Antibody (393314) [mFluor Violet 450 SE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Claudin-12 Antibody (393314) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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