FADD Antibody (OTI1C11) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

Applications for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FADD

Fas-associating protein with death domain (FADD) is an adaptor protein involved in the apoptosis induced by Fas and TNF-R1, and mitogen induced cell proliferation (1). FADD consists of death domain (DD) at the C-terminal and death effector domain (DED) at the N-terminal (2). DD interacts with Fas and TNF-R1, which exposes the DED portion on the FADD. Unmasked DED binds to the DED of pro-caspase-8, which activates the cysteine protease cascade (3). The development of autoimmune lymphoproliferative (lpr) diseases has been linked to inactivation of Fas-FADD interaction (4). Also, the deficiency in FADD can inhibit TRAIL-induced cell apoptosis.

Long Name

Fas-associated Death Domain Protein

Alternate Names

MORT1

Gene Symbol

FADD

Additional FADD Products

Product Documents for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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Flow Cytometry

FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-71387MFV500

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all FADD Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Scientific Data Images for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

FADD Antibody (OTI1C11) [mFluor Violet 500 SE] -

Applications for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

Flow Cytometry

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: FADD

Long Name

Alternate Names

Gene Symbol

Additional FADD Products

Product Documents for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for FADD Antibody (OTI1C11) [mFluor Violet 500 SE]

CONTACT INFORMATION

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