Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: FADD

Fas-associating protein with death domain (FADD) is an adaptor protein involved in the apoptosis induced by Fas and TNF-R1, and mitogen induced cell proliferation (1). FADD consists of death domain (DD) at the C-terminal and death effector domain (DED) at the N-terminal (2). DD interacts with Fas and TNF-R1, which exposes the DED portion on the FADD. Unmasked DED binds to the DED of pro-caspase-8, which activates the cysteine protease cascade (3). The development of autoimmune lymphoproliferative (lpr) diseases has been linked to inactivation of Fas-FADD interaction (4). Also, the deficiency in FADD can inhibit TRAIL-induced cell apoptosis.

Long Name

Fas-associated Death Domain Protein

Alternate Names

MORT1

Gene Symbol

FADD

Additional FADD Products

Product Documents for FADD Antibody (OTI1C11) [PE/Atto594]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for FADD Antibody (OTI1C11) [PE/Atto594]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

FADD Antibody (OTI1C11) [PE/Atto594]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-71387PEATT594

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all FADD Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for FADD Antibody (OTI1C11) [PE/Atto594]

Flow Cytometry

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: FADD

Long Name

Alternate Names

Gene Symbol

Additional FADD Products

Product Documents for FADD Antibody (OTI1C11) [PE/Atto594]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for FADD Antibody (OTI1C11) [PE/Atto594]

CONTACT INFORMATION

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