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Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07899

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Functional, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # DATK32

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

TK1 cells

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899]

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899]

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899] - Separation of murine LPAM-1 positive cells (red-filled) from LPAM-1 negative cells (black-dashed) in flow cytometry analysis (surface staining) of murine splenocyte suspension stained using Rat Monoclonal Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) (concentration in sample 2 ug/ml) DAR APC.
Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899]

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899]

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free [NBP3-07899] - Flow cytometry surface staining pattern of murine splenocyte suspension stained usingRat Monoclonal Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) (concentration in sample 2 ug/ml) DAR APC.

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Functional application: Blocking of cell adhesion

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4), 0.2 um filter sterilized

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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