Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07899JF549

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Flow Cytometry, Functional, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Janelia Fluor 549

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # DATK32

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 4 beta 7/LPAM-1 Antibodies »

Product Summary for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) [Janelia Fluor® 549]

Immunogen

TK1 cells

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) [Janelia Fluor® 549]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (DATK32) [Janelia Fluor® 549]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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