MAdCAM-1 Antibody (OTI1A5) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72568F

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-45706

Alexa Fluor 350

NBP2-72568AF350

Alexa Fluor 405

NBP2-72568AF405

Alexa Fluor 488

NBP2-72568AF488

Alexa Fluor 532

NBP2-72568AF532

Alexa Fluor 594

NBP2-72568AF594

Alexa Fluor 647

NBP2-72568AF647

Alexa Fluor 700

NBP2-72568AF700

Alexa Fluor 750

NBP2-72568AF750

Allophycocyanin

NBP2-72568APC

Biotin

NBP2-72568B

CoraFluor 1

NBP2-72568CL1

DyLight 350

NBP2-72568UV

DyLight 405

NBP2-72568V

DyLight 488

NBP2-72568G

DyLight 550

NBP2-72568R

DyLight 594

NBP2-72568DL594

DyLight 650

NBP2-72568C

DyLight 680

NBP2-72568FR

DyLight 755

NBP2-72568IR

HRP

NBP2-72568H

Janelia Fluor 525

NBP2-72568JF525

Janelia Fluor 549

NBP2-72568JF549

Janelia Fluor 585

NBP2-72568JF585

Janelia Fluor 635

NBP2-72568JF635

Janelia Fluor 646

NBP2-72568JF646

Janelia Fluor 669

NBP2-72568JF669

PE

NBP2-72568PE

PerCP

NBP2-72568PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-72568

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunofluorescence

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG_2B Clone # OTI1A5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAdCAM-1 Antibodies »

Product Summary for MAdCAM-1 Antibody (OTI1A5) [FITC]

Immunogen

Full length recombinant protein of human MAdCAM-1 (NP_570116) produced in HEK293T cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for MAdCAM-1 Antibody (OTI1A5) [FITC]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MAdCAM-1

Mucosal vascular addressin-1 (MAdCAM-1) is a type I transmembrane glycoprotein expressed at high levels on high endothelial venules (HEV) of Peyer's patches and mesenteric lymph nodes, and on flat walled venules within the gut lamina propria. It is also expressed on sinus-lining cells in the spleen. (1-3) The countereceptor or "homing receptor" for MAdCAM-1 is alpha4beta7 integrin (also known as LPAM-1). MAdCAM-1 is also a facultative ligand for CD62L/L-selectin. (4, 5) The monoclonal antibody MECA-367 binds to the first domain of MAdCAM-1 and blocks MAdCAM-1-dependent binding in vitro and lymphocyte homing to Peyer's patch HEV in vivo. (1, 2, 4)

Long Name

Mucosal Addressin Cell Adhesion Molecule 1

Alternate Names

MAdCAM1

Gene Symbol

MADCAM1

Additional MAdCAM-1 Products

Product Documents for MAdCAM-1 Antibody (OTI1A5) [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MAdCAM-1 Antibody (OTI1A5) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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