Mitofusin 1 Antibody (11E9-1H12) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-71775JF646
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated, Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG2b Kappa Clone # 11E9-1H12
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Mitofusin 1 Antibody (11E9-1H12) [Janelia Fluor® 646]
Immunogen
Mouse Mitofusin 1
Reactivity Notes
Rat reactivity reported in scientific literature (PMID: 23658809). Human reactivity reported in scientific literature (PMID: 24710686, 24928681).
Localization
Mitochondrion outer membrane; Multi-pass membrane protein
Marker
Mitochondrial Fusion Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2b Kappa
Applications for Mitofusin 1 Antibody (11E9-1H12) [Janelia Fluor® 646]
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Knockout Validated
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Mitofusin 1
Mitochondrial fusion occurs in many cell types and is a fundamental component of mitochondria morphology, which is balanced between fusion and fission. Mitochondrial dysfunction is a major cause of neuronal death in degenerative disorders, such as Parkinson's disease, and can be triggered by an imbalance in the dynamic equilibrium between mitochondrial fission and fusion.
Alternate Names
hfzo1, hfzo2, MFN1
Gene Symbol
MFN1
Additional Mitofusin 1 Products
Product Documents for Mitofusin 1 Antibody (11E9-1H12) [Janelia Fluor® 646]
Product Specific Notices for Mitofusin 1 Antibody (11E9-1H12) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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