NHE3/SLC9A3 [p Ser605] Antibody (10A8) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-74678B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NB110-74678

Alexa Fluor 350

NB110-74678AF350

Alexa Fluor 405

NB110-74678AF405

Alexa Fluor 488

NB110-74678AF488

Alexa Fluor 532

NB110-74678AF532

Alexa Fluor 594

NB110-74678AF594

Alexa Fluor 647

NB110-74678AF647

Alexa Fluor 700

NB110-74678AF700

Alexa Fluor 750

NB110-74678AF750

CoraFluor 1

NB110-74678CL1

DyLight 350

NB110-74678UV

DyLight 405

NB110-74678V

DyLight 488

NB110-74678G

DyLight 550

NB110-74678R

DyLight 594

NB110-74678DL594

DyLight 650

NB110-74678C

DyLight 680

NB110-74678FR

DyLight 755

NB110-74678IR

FITC

NB110-74678F

HRP

NB110-74678H

Janelia Fluor 525

NB110-74678JF525

Janelia Fluor 549

NB110-74678JF549

Janelia Fluor 585

NB110-74678JF585

Janelia Fluor 635

NB110-74678JF635

Janelia Fluor 646

NB110-74678JF646

Janelia Fluor 669

NB110-74678JF669

mFluor Violet 450 SE

NB110-74678MFV450

mFluor Violet 500 SE

NB110-74678MFV500

mFluor Violet 610 SE

NB110-74678MFV610

Forumulation

Catalog #

Azide and BSA Free

NBP2-80876

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Mouse, Rat, Porcine, Opossum, Primate, Rabbit

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG_2B Clone # 10A8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NHE3/SLC9A3 Antibodies »

Product Summary for NHE3/SLC9A3 [p Ser605] Antibody (10A8) [Biotin]

Immunogen

Synthetic peptide made to a region surrounding the Serine 605 portion of rat NHE3. [UniProt# P26433]

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID: 29510506).

Modification

p Ser605

Localization

Membrane.

Specificity

This antibody detects NHE3 posphorylated at serine 605, and does not cross-react with the non-phosphopeptide.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for NHE3/SLC9A3 [p Ser605] Antibody (10A8) [Biotin]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NHE3/SLC9A3

NHE3 is a member of the Sodium/Hydrogen exchanger family that plays a crucial role in acid-base and volume homeostasis by mediating the majority of sodium and bicarbonate reabsorption in the proximal tubule of the kidney. Two PKA consensus sites have been discovered in rat NHE3, serine 552 and serine 605. Research suggests that dopamine-induced phosphorylation of these consensus sites inhibit NHE3.

Long Name

Sodium/Hydrogen Exchanger 3

Alternate Names

SLC9A3

Gene Symbol

SLC9A3

Additional NHE3/SLC9A3 Products

Product Documents for NHE3/SLC9A3 [p Ser605] Antibody (10A8) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for NHE3/SLC9A3 [p Ser605] Antibody (10A8) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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