Rat TIMP-1 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF580
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Cys24-Ala217
Accession # P30120
Specificity
Clonality
Host
Isotype
Applications for Rat TIMP-1 Biotinylated Antibody
Western Blot
Sample: Recombinant Rat TIMP-1 (Catalog # 580-RT)
Rat TIMP-1 Sandwich Immunoassay
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TIMP-1
Tissue inhibitors of metalloproteinases (TIMPs) are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family: TIMP-1, TIMP-2, TIMP-3, and TIMP-4. TIMP-1 is a glycoprotein with a molecular mass of 32‑34 kDa produced by a wide range of cell types. TIMP-1 inhibits active MMP-mediated proteolysis by forming an N-terminal, non-covalent binary complex with the MMP active site. TIMP-1 also associates C-terminally with pro-MMP-9 in a complex which may play a role in regulating activation. Independent of MMPs, TIMP-1 has been shown to have a role in tissue homeostasis.
Long Name
Alternate Names
Gene Symbol
UniProt
Additional TIMP-1 Products
Product Documents for Rat TIMP-1 Biotinylated Antibody
Product Specific Notices for Rat TIMP-1 Biotinylated Antibody
For research use only