TIM-1/KIM-1/HAVCR Antibody (3B3) [Allophycocyanin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81119APC

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize, ELISA, Flow Cytometry, Functional, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Surface Plasmon Resonance

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # 3B3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TIM-1/KIM-1/HAVCR Antibodies »

Product Specifications

Immunogen

This antibody was raised by immunising female Lewis strain rats (Harlan Sprague-Dawley) subcutaneously with mouse TIM-1/KIM-1/HAVCR-Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1/KIM-1/HAVCR-Ig in PBS.

Specificity

This antibody is specific for murine TIM-1/KIM-1/HAVCR, a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. TIM-1/KIM-1/HAVCR has been found on activated CD4+ T cells, mast cells, and a subset of B cells. TIM-1/KIM-1/HAVCR is involved in renal injury, tissue homeostasis, and T cell costimulation, and promotes the differentiation of Th2 cells and the production of IL-4. TIM-1/KIM-1/HAVCR can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for TIM-1/KIM-1/HAVCR Antibody (3B3) [Allophycocyanin]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Surface Plasmon Resonance

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TIM-1/KIM-1/HAVCR

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Long Name

T Cell Immunoglobulin Mucin-1

Alternate Names

CD365, HAVCR1, KIM-1, TIM1

Gene Symbol

HAVCR1

Additional TIM-1/KIM-1/HAVCR Products

Product Documents for TIM-1/KIM-1/HAVCR Antibody (3B3) [Allophycocyanin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TIM-1/KIM-1/HAVCR Antibody (3B3) [Allophycocyanin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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