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B-Raf Products

The Raf serine/threonine kinases are effectors of Ras that function as MAP3Ks in the ERK phosphorylation cascade. Mammals express three Raf proteins: Raf-1 (C-Raf); A-Raf; and B-Raf, strongly expressed in fetal brain and adult cerebrum. Mice with a targeted disruption of the B-raf gene die of vascular defects during mid-gestation. B-raf mutations have been found in two-thirds of malignant melanomas, with the single substitution V599E in the kinase domain the most frequent occurrence.

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54 results for "B-Raf" in Products

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54 results for "B-Raf" in Products

B-Raf Products

The Raf serine/threonine kinases are effectors of Ras that function as MAP3Ks in the ERK phosphorylation cascade. Mammals express three Raf proteins: Raf-1 (C-Raf); A-Raf; and B-Raf, strongly expressed in fetal brain and adult cerebrum. Mice with a targeted disruption of the B-raf gene die of vascular defects during mid-gestation. B-raf mutations have been found in two-thirds of malignant melanomas, with the single substitution V599E in the kinase domain the most frequent occurrence.

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Applications: WB, Simple Western
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Simple Western
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, WB
Reactivity: Human
Applications: ELISA
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human, Rat
Applications: WB
Reactivity: Human
Applications: WB
Applications: AC
Applications: IHC, WB, ICC/IF, Flow, IP, CyTOF-ready
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, WB, ICC/IF, Flow, IP, CyTOF-ready
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, WB, ICC/IF, Flow, IP, CyTOF-ready
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, ICC/IF, Flow, IP
Reactivity: Human, Mouse, Rat, Monkey
Applications: IHC, WB
Reactivity: Human
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