Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
9 results for "Caspase-3" in Products
9 results for "Caspase-3" in Products
Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | WB, IHC, ICC, ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IP, KO |
| Assay Range: | 219 - 14,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P42574 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #84803 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1112I |
| Applications: | Dual ISH-IHC, ICC |
| Source: | E. coli |
| Accession #: | AAA65015 |
| Applications: | EnzAct |