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CrkL Products

CrkL is a widely-expressed 39 kD adaptor protein that belongs to the Crk protein family and is abundantly expressed in cells of hematopoetic origin. Through its SH2 and SH3 domains CrkL initiates interactions with numerous downstream proteins such as CBL, Cas, Paxillin, C3G, SOS, PI3K, c-Abl and BCR/Abl. It is involved in processes such as adhesion, migration and immune responses. Furthermore, CrkL plays an essential role in Chronic Myelogenous Leukemia and is constitutively phosphorylated by the Bcr-Abl kinase in this disease.

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23 results for "CrkL" in Products

23 results for "CrkL" in Products

CrkL Products

CrkL is a widely-expressed 39 kD adaptor protein that belongs to the Crk protein family and is abundantly expressed in cells of hematopoetic origin. Through its SH2 and SH3 domains CrkL initiates interactions with numerous downstream proteins such as CBL, Cas, Paxillin, C3G, SOS, PI3K, c-Abl and BCR/Abl. It is involved in processes such as adhesion, migration and immune responses. Furthermore, CrkL plays an essential role in Chronic Myelogenous Leukemia and is constitutively phosphorylated by the Bcr-Abl kinase in this disease.

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Applications: WB
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF, Func, KD
Reactivity: Human, Mouse
Applications: WB, Simple Western
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Human
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB, ELISA, ICC/IF, Flow
Reactivity: Human, Mouse
Applications: IHC, WB
Reactivity: Human
Applications: WB, ELISA, Flow
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat, Chicken, Xenopus
Applications: WB
Reactivity: Human, Mouse, Rat, Chicken, Xenopus
Applications: WB
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat
Applications: ELISA
Applications: WB
Applications: ELISA
Applications: PAGE
Applications: AC
Applications: AC
Applications: AC
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