Endocan/ESM-1 Products
Endocan, also known as Endothelial Cell-specific Molecule-1 (ESM-1) and IGFBP-rp6, is a secreted cysteine-rich dermatan sulfate proteoglycan. It is primarily expressed by endothelial cells within the vascular network of the kidney and in the alveolar walls of the lung. Endocan expression is upregulated by TNF-alpha, IL-1 beta and LPS, and downregulated by IFN-gamma. Endocan binds LFA-1 on human lymphocytes, monocytes and Jurkat cells, inhibiting its binding to ICAM-1 and reducing LFA-1-mediated leukocyte activation. Elevated circulating Endocan levels have been reported in patients with lung cancer and severe sepsis.
54 results for "Endocan/ESM-1" in Products
54 results for "Endocan/ESM-1" in Products
Endocan/ESM-1 Products
Endocan, also known as Endothelial Cell-specific Molecule-1 (ESM-1) and IGFBP-rp6, is a secreted cysteine-rich dermatan sulfate proteoglycan. It is primarily expressed by endothelial cells within the vascular network of the kidney and in the alveolar walls of the lung. Endocan expression is upregulated by TNF-alpha, IL-1 beta and LPS, and downregulated by IFN-gamma. Endocan binds LFA-1 on human lymphocytes, monocytes and Jurkat cells, inhibiting its binding to ICAM-1 and reducing LFA-1-mediated leukocyte activation. Elevated circulating Endocan levels have been reported in patients with lung cancer and severe sepsis.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | Q9NQ30 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #6D4 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Endocan/ESM-1 Antibody (6D4) [H00011082-M02]](https://resources.bio-techne.com/images/products/Endocan-ESM-1-Antibody-6D4-Western-Blot-H00011082-M02-img0008.jpg "Western Blot: Endocan/ESM-1 Antibody (6D4) [H00011082-M02]")
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #220008 |
| Applications: | WB, Neut |
| Assay Range: | 23.4 - 1,500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q9QYY7 |
| Applications: | BA |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: Endocan/ESM-1 Overexpression Lysate [NBL1-10343]](https://resources.bio-techne.com/images/products/Esm1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10343-img0002.jpg "Western Blot: Endocan/ESM-1 Overexpression Lysate [NBL1-10343]")
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C7 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #E1 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0079-5J44 |
| Applications: | WB |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies