Fc gamma RIIIA/CD16a Products
Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils.
Surface expression requires interaction with an accessory chain, either the common gamma chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.
Products:
202 results for "Fc gamma RIIIA/CD16a" in Products
202 results for "Fc gamma RIIIA/CD16a" in Products
Fc gamma RIIIA/CD16a Products
Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils.
Surface expression requires interaction with an accessory chain, either the common gamma chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.
Products:
Analyzed by SEC-MALS, Isoform V176, His-tag
Source: | NS0 |
Accession #: | AAH17865 |
Applications: | Bind |
Recombinant Monoclonal
Reactivity: | Human |
Details: | Rabbit Monoclonal Clone #BLR162J |
Applications: | IHC, WB, ICC/IF |
Low-affinity V176F polymorphic variant
Source: | HEK293 |
Accession #: | P08637 |
Applications: | BA |
Reactivity: | Human, Primate, Porcine |
Details: | Mouse IgM Monoclonal Clone #MEM-168 |
Applications: | Flow |
Biotinylated Isoform V176
Source: | HEK293 |
Accession #: | AAH17865.1 |
Applications: | BA, BA |
Reactivity: | Human, Primate |
Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
Applications: | IHC, Flow, IP, CyTOF-ready |
Source: | NS0 |
Accession #: | NP_997486 |
Applications: | BA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #2G10A9 |
Applications: | WB, ELISA, Flow |
Reactivity: | Human, Cynomolgus Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ELISA |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #DJ130c |
Applications: | IHC, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Reactivity: | Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #C16/1045 |
Applications: | ICC/IF, Flow, CyTOF-ready |
Recombinant monoclonal antibody expressed in HEK293F cells
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #28C11 |
Applications: | ELISA, ICC/IF |
Applications: | WB |
Applications: | WB |
Reactivity: | Human, Primate |
Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
Applications: | IHC, Flow, IP, CyTOF-ready |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ELISA |
Applications: | AC |
Reactivity: | Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, IP |
Reactivity: | Human, Cynomolgus Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ELISA |