GRIN2B/NMDAR2B Products
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
22 results for "GRIN2B/NMDAR2B" in Products
22 results for "GRIN2B/NMDAR2B" in Products
GRIN2B/NMDAR2B Products
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Reactivity: | Human, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Serum Polyclonal |
| Applications: | WB |
Non-competitive NMDA antagonist; acts at ion channel site
| Alternate Names: | Dizocilpine |
| Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Purity: | ≥99% (HPLC) |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% (HPLC) |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine
| Chemical Name: | (R)-(-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
NMDA antagonist; acts at ion channel site
| Chemical Name: | 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride |
Non-competitive NMDA antagonist; also σ ligand
| Chemical Name: | (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate |
| Purity: | ≥99% (HPLC) |
Glucosidase α inhibitor (intestinal)
| Alternate Names: | Bay-g 5421 |
| Chemical Name: | O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose |
Potent NMDA antagonist; acts at glycine site
| Chemical Name: | 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Specific σ ligand, NMDA antagonist
| Chemical Name: | 4-Phenyl-1-(4-phenylbutyl)piperidine maleate |
| Purity: | ≥99% (HPLC) |
Highly potent NMDA antagonist
| Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
| Purity: | ≥99% (HPLC) |
Positive allosteric modulator of NMDA receptors; acts in transmembrane domain
| Chemical Name: | 4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; acts at the glycine site
| Alternate Names: | GV 150526A |
| Chemical Name: | 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt |
| Purity: | ≥98% (HPLC) |
GluN2B-selective NMDA antagonist
| Alternate Names: | PD 174494,Ro 63-1908 |
| Chemical Name: | 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective NMDA antagonist
| Chemical Name: | (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid |
| Purity: | ≥99% (HPLC) |
NMDA antagonist; acts at glycine site
| Chemical Name: | 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone |
| Purity: | ≥99% (HPLC) |
Potent and noncompetitive NMDA antagonist
| Alternate Names: | CNS 1102 |
| Chemical Name: | N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride |
| Purity: | ≥98% (HPLC) |
