IL-18/IL-1F4: ELISA Kits
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
17 results for "IL-18/IL-1F4 ELISA Kits" in Products
17 results for "IL-18/IL-1F4 ELISA Kits" in Products
IL-18/IL-1F4: ELISA Kits
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
| Sensitivity: | 5.15 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Assay Range: | 11.7 - 750 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 25 pg/mL |
| Applications: | ELISA |
| Assay Range: | 25.6 - 1,000 pg/mL |
Human IL-18/IL-1F4 Quantikine ELISA Kit is now available!
| Sensitivity: | 12.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 25.6 - 1,000 pg/mL |
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
For use with catalog number DL180
| Applications: | Ctrl |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 6.25 - 400 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA, NULL |
| Assay Range: | 0.313 - 20 ng/mL |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Applications: | ELISA |
| Applications: | ELISA |
