LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
Products:
167 results for "LDLR" in Products
167 results for "LDLR" in Products
LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
Products:
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Func, KO, +1 More |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #SJ0197 |
Applications: | IHC, WB, ICC/IF, Flow |
Recombinant monoclonal antibody expressed in HEK293F cells
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2B10 |
Applications: | IHC, ICC/IF, ELISA, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ICC/IF, ELISA, Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #004 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #004 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #301 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #301 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ICC/IF, ELISA, Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IP |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #301 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #301 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ICC/IF, ELISA, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #004 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #004 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #004 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ICC/IF, ELISA, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ELISA, ICC/IF, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #032 |
Applications: | ELISA, ICC/IF, Flow |