MeCP2 Products
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
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86 results for "MeCP2" in Products
86 results for "MeCP2" in Products
MeCP2 Products
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
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Applications: IHC, WB, ICC/IF, IP
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat,
Monkey
Reactivity: | Human, Mouse, Rat, Monkey |
Details: | Chicken IgY Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ELISA
Reactivity:
Human
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #1B11 |
Applications: | IHC, WB, ELISA |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #4F11 |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ELISA
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2a Kappa Monoclonal Clone #4B6 |
Applications: | IHC, WB, ELISA |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat,
Monkey
Reactivity: | Human, Mouse, Rat, Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2B Monoclonal Clone #5H12 |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, ICC/IF
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ICC/IF |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: | WB, ELISA, MA, AP |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Applications: WB
Reactivity:
Mouse,
Rat
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Applications: IHC, WB
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Applications: | WB, ELISA, MA, AP |
Applications: | WB |
Applications: | ELISA |
Applications: | ELISA |
Applications: | AC |
Applications: | AC |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #4F11 |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat,
Monkey
Reactivity: | Human, Mouse, Rat, Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #4F11 |
Applications: | IHC, WB, ICC/IF |