Ras GTPase Inhibitors Products
Ras GTPases are prototypical members of the RAS superfamily. They are responsible for regulating cytosolic signaling pathways involved in gene expression as well as regulation of cell proliferation, differentiation and survival.
Products:
7 results for "Ras GTPase Inhibitors" in Products
7 results for "Ras GTPase Inhibitors" in Products
Ras GTPase Inhibitors Products
Ras GTPases are prototypical members of the RAS superfamily. They are responsible for regulating cytosolic signaling pathways involved in gene expression as well as regulation of cell proliferation, differentiation and survival.
Products:
Potent farnesyl diphosphate (FPP) synthase inhibitor
| Alternate Names: | Zometa |
| Chemical Name: | [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid |
| Purity: | ≥98% (HPLC) |
Ras signaling inhibitor; inhibits Ack1 and GCK
| Chemical Name: | N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
| Chemical Name: | 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective KRASG12C inhibitor
| Alternate Names: | Sotorasib |
| Chemical Name: | (1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one |
| Purity: | ≥98% (HPLC) |
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
| Chemical Name: | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone |
| Purity: | ≥98% (HPLC) |
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
| Chemical Name: | N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Mutation-selective inhibitor of KRASG12C
| Alternate Names: | Adagrasib |
| Chemical Name: | 4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2S)-2-piperazineacetonitrile |
| Purity: | ≥98% (HPLC) |
