Ras GTPase Inhibitors Products
Ras GTPases are prototypical members of the RAS superfamily. They are responsible for regulating cytosolic signaling pathways involved in gene expression as well as regulation of cell proliferation, differentiation and survival.
Products:
6 results for "Ras GTPase Inhibitors" in Products
6 results for "Ras GTPase Inhibitors" in Products
Ras GTPase Inhibitors Products
Ras GTPases are prototypical members of the RAS superfamily. They are responsible for regulating cytosolic signaling pathways involved in gene expression as well as regulation of cell proliferation, differentiation and survival.
Products:
Ras signaling inhibitor; inhibits Ack1 and GCK
| Chemical Name: | N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
Potent farnesyl diphosphate (FPP) synthase inhibitor
| Alternate Names: | Zometa |
| Chemical Name: | [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid |
| Purity: | ≥98% (HPLC) |
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
| Chemical Name: | 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
| Chemical Name: | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone |
| Purity: | ≥98% (HPLC) |
Mutation-selective inhibitor of KRASG12C
| Alternate Names: | Adagrasib |
| Chemical Name: | 4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2S)-2-piperazineacetonitrile |
| Purity: | ≥98% (HPLC) |
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
| Chemical Name: | N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
