Synthetic Cathepsin Inhibitors: Small Molecules and Peptides
Cathepsin A, also known as lyososomal carboxypeptidase A, is a member of the serine carboxypeptidase family. Cathepsin A is a multifunctional enzyme that expresses deaminidase and esterase activities at neutral pH and carboxypeptidase activity at acidic pH. Cathepsin A is synthesized as a single-chain precursor and processed into heavy (32 kDa) and light (20 kDa) chains, which are linked by disulfide bonds.
7 results for "Synthetic Cathepsin Inhibitors Small Molecules and Peptides" in Products
7 results for "Synthetic Cathepsin Inhibitors Small Molecules and Peptides" in Products
Synthetic Cathepsin Inhibitors: Small Molecules and Peptides
Cathepsin A, also known as lyososomal carboxypeptidase A, is a member of the serine carboxypeptidase family. Cathepsin A is a multifunctional enzyme that expresses deaminidase and esterase activities at neutral pH and carboxypeptidase activity at acidic pH. Cathepsin A is synthesized as a single-chain precursor and processed into heavy (32 kDa) and light (20 kDa) chains, which are linked by disulfide bonds.
Cathepsin inhibitor; interferes with autolysosomal digestion
| Chemical Name: | (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester |
| Purity: | ≥98% (HPLC) |
Selective cathepsin B inhibitor
| Chemical Name: | N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline |
| Purity: | ≥98% (HPLC) |
Potent cathepsin C inhibitor
| Chemical Name: | 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano[1,1'-biphenyl]-4-yl)ethyl]tetrahydro-2H-pyran-4-carboxamide |
| Purity: | ≥98% (HPLC) |
Cathepsin L inhibitor
| Chemical Name: | N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide |
| Purity: | ≥97% (HPLC) |
Potent and irreversible cysteine protease inhibitor
| Chemical Name: | (2S,3S)-3-[[[(1S)-1-[[[4-(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent cathepsin K inhibitor
| Chemical Name: | N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective cathepsin K inhibitor
| Chemical Name: | N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide |
| Purity: | ≥98% (HPLC) |
