VE-Cadherin Products
VE-Cadherin, also known as Cadherin-5 and CD144, is a member of the atypical/type II subgroup of Cadherin homophilic adhesion proteins. A 90 kDa portion of the VE-Cadherin ECD can be shed in a metalloproteinase-dependent mechanism and may function as a VE-Cadherin antagonist. VE-Cadherin is expressed on the surface of vascular endothelial cells (EC) from early in embryogenesis through adulthood as well as in the placenta, on hematopoietic cell progenitors, and on a subpopulation of hematopoietic stem cells. It is a major protein component of adherens junctions between cells of the endothelium.
VE-Cadherin supports the extension and stabilization of existing vascular sprouts. VE-Cadherin also regulates or is regulated by VEGF R2, type I and type II TGF-beta receptors, and other endothelial junction proteins, such as JAM-C, Claudin-5, and N-Cadherin. Elevated levels of soluble VE-Cadherin are found in the serum of myocardial infarction, angina pectoris, rheumatoid arthritis, and colorectal cancer patients.
Products:
292 results for "VE-Cadherin" in Products
292 results for "VE-Cadherin" in Products
VE-Cadherin Products
VE-Cadherin, also known as Cadherin-5 and CD144, is a member of the atypical/type II subgroup of Cadherin homophilic adhesion proteins. A 90 kDa portion of the VE-Cadherin ECD can be shed in a metalloproteinase-dependent mechanism and may function as a VE-Cadherin antagonist. VE-Cadherin is expressed on the surface of vascular endothelial cells (EC) from early in embryogenesis through adulthood as well as in the placenta, on hematopoietic cell progenitors, and on a subpopulation of hematopoietic stem cells. It is a major protein component of adherens junctions between cells of the endothelium.
VE-Cadherin supports the extension and stabilization of existing vascular sprouts. VE-Cadherin also regulates or is regulated by VEGF R2, type I and type II TGF-beta receptors, and other endothelial junction proteins, such as JAM-C, Claudin-5, and N-Cadherin. Elevated levels of soluble VE-Cadherin are found in the serum of myocardial infarction, angina pectoris, rheumatoid arthritis, and colorectal cancer patients.
Products:
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, Dual ISH-IHC |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, Flow, CyTOF-ready, ICC |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | WB, Flow, CyTOF-ready, ICC |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #162709 |
Applications: | Flow |
Sensitivity: | 0.236 ng/mL |
Applications: | ELISA |
Assay Range: | 1.56 - 100 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Clone BV9 was used by HLDA to establish CD designation.
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #BV9 |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
Reactivity: | Human, Mouse, Rabbit |
Details: | Rat IgG2B Monoclonal Clone #BV14 |
Applications: | IHC, WB, ICC/IF, IP |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #162709 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #123433 |
Applications: | WB |
Source: | NS0 |
Accession #: | P33151 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | WB, Flow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #162709 |
Applications: | Flow |
Assay Range: | 0.312 - 20 ng/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #162709 |
Applications: | Flow |
Source: | NS0 |
Accession #: | 2208309A |
Applications: | BA |
For use with catalog number DCADV0
Applications: | ELISA, Ctrl |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human, Rat |
Details: | Mouse IgG1 Monoclonal Clone #3D5C7 |
Applications: | WB, ELISA, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #123413 |
Applications: | Flow |