PIAS3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77160

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all PIAS3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human PIAS3. The immunogen is located within amino acids 410 - 460 of PIAS3. Amino Acid Squence: SPVQGGDPSENK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PIAS3 Antibody - BSA Free

Western Blot: PIAS3 AntibodyBSA Free [NBP1-77160]

Western Blot: PIAS3 AntibodyBSA Free [NBP1-77160]

Western Blot: PIAS3 Antibody [NBP1-77160] - K562 cell lysate with PIAS3 antibody at 1 ug/mL.
Immunohistochemistry-Paraffin: PIAS3 Antibody - BSA Free [NBP1-77160]

Immunohistochemistry-Paraffin: PIAS3 Antibody - BSA Free [NBP1-77160]

Immunohistochemistry-Paraffin: PIAS3 Antibody [NBP1-77160] - Human breast carcinoma tissue with PIAS3 antibody at 5 ug/mL.
Western Blot: PIAS3 AntibodyBSA Free [NBP1-77160]

Western Blot: PIAS3 AntibodyBSA Free [NBP1-77160]

Western Blot: PIAS3 Antibody [NBP1-77160] - Western for PIAS3 in THP1 macrophage cells, Image from verified customer review.
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Applications for PIAS3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Reviewed Applications

Read 1 review rated 4 using NBP1-77160 in the following applications:

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIAS3

The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays multiple roles in different tissue and cell types.

Long Name

Protein Inhibitor of Activated STAT 3

Alternate Names

ZMIZ5

Gene Symbol

PIAS3

UniProt

NP_006090 (Human)

Additional PIAS3 Products

Product Documents for PIAS3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PIAS3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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