Histone H2AX [p Ser139] Antibody (RM224) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26030H

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-18533

Alexa Fluor 350

NBP3-26030AF350

Alexa Fluor 405

NBP3-26030AF405

Alexa Fluor 488

NBP3-26030AF488

Alexa Fluor 532

NBP3-26030AF532

Alexa Fluor 594

NBP3-26030AF594

Alexa Fluor 647

NBP3-26030AF647

Alexa Fluor 700

NBP3-26030AF700

Alexa Fluor 750

NBP3-26030AF750

Allophycocyanin

NBP3-26030APC

Biotin

NBP3-26030B

CoraFluor 1

NBP3-26030CL1

DyLight 350

NBP3-26030UV

DyLight 405

NBP3-26030V

DyLight 488

NBP3-26030G

DyLight 550

NBP3-26030R

DyLight 594

NBP3-26030DL594

DyLight 650

NBP3-26030C

DyLight 680

NBP3-26030FR

DyLight 755

NBP3-26030IR

FITC

NBP3-26030F

Janelia Fluor 525

NBP3-26030JF525

Janelia Fluor 549

NBP3-26030JF549

Janelia Fluor 646

NBP3-26030JF646

Janelia Fluor 669

NBP3-26030JF669

mFluor Violet 450 SE

NBP3-26030MFV450

mFluor Violet 500 SE

NBP3-26030MFV500

mFluor Violet 610 SE

NBP3-26030MFV610

PE

NBP3-26030PE

PerCP

NBP3-26030PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-26030

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Vertebrate

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Multiplex Immunoassay, Western Blot

Label

HRP

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM224

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Histone H2AX Antibodies »

Product Specifications

Immunogen

A phospho-peptide corresponding to Histone H2AX [Ser139]

Modification

p Ser139

Specificity

This antibody reacts to Histone H2AX only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Histone H2AX [p Ser139] Antibody (RM224) [HRP]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Multiplex Immunoassay

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Histone H2AX

Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.

Alternate Names

H2AFX

Gene Symbol

H2AX

Additional Histone H2AX Products

Product Documents for Histone H2AX [p Ser139] Antibody (RM224) [HRP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Histone H2AX [p Ser139] Antibody (RM224) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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