Adenosine A3 R: Small Molecules and Peptides
Adenosine A3 Receptor (ADORA3) belongs to the family of adenosine receptors, which are G protein-coupled receptors involved in a variety of intracellular signaling pathways and physiological functions. ADORA3 mediates a sustained cardioprotective function during cardiac ischemia. It is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury. ADORA3 has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death.
14 results for "Adenosine A3 R Small Molecules and Peptides" in Products
14 results for "Adenosine A3 R Small Molecules and Peptides" in Products
Adenosine A3 R: Small Molecules and Peptides
Adenosine A3 Receptor (ADORA3) belongs to the family of adenosine receptors, which are G protein-coupled receptors involved in a variety of intracellular signaling pathways and physiological functions. ADORA3 mediates a sustained cardioprotective function during cardiac ischemia. It is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury. ADORA3 has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death.
Endogenous adenosine receptor agonist
| Chemical Name: | 9-β-D-Ribofuranosyl-9H-purin-6-amine |
| Purity: | ≥99% (HPLC) |
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
High affinity adenosine agonist
| Alternate Names: | 5'-N-Ethylcarboxamidoadenosine |
| Chemical Name: | 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide |
| Purity: | ≥98% (HPLC) |
Potent adenosine receptor antagonist
| Chemical Name: | 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine |
| Purity: | ≥99% (HPLC) |
Highly selective A3 agonist
| Chemical Name: | 1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide |
| Purity: | ≥98% (HPLC) |
Adenosine receptor agonist
| Alternate Names: | 2-CADO |
| Chemical Name: | 6-Amino-2-chloropurine riboside |
| Purity: | ≥98% (HPLC) |
Potent and selective A3 adenosine receptor antagonist
| Chemical Name: | N-[4-(3,5-Dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-3-pyridinecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity selective A3 agonist
| Chemical Name: | 2-(1-Hexynyl)-N-methyladenosine |
| Purity: | ≥99% (HPLC) |
Adenosine receptor antagonist
| Chemical Name: | 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid |
| Purity: | ≥98% (HPLC) |
A3 selective agonist
| Alternate Names: | CF 101,Piclidenoson |
| Chemical Name: | 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide |
| Purity: | ≥97% (HPLC) |
Adenosine receptor antagonist
| Alternate Names: | Xanthine amine congener |
| Chemical Name: | N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Highly potent and selective hA3 antagonist
| Chemical Name: | N-[9-Chloro-2-(2-furanyl)[1,2,4]-triazolo[1,5-c]quinazolin-5-yl]benzene acetamide |
| Purity: | ≥98% (HPLC) |
Potent, highly selective hA3 receptor antagonist/inverse agonist
| Chemical Name: | (8R)-8-Ethyl-1,4,7,8-tetrahydro-4-methyl-2-(2,3,5-trichlorophenyl)-5H-imidazo[2,1-i]purin-5-one monohydrochloride |
| Purity: | ≥98% (HPLC) |
Potent, highly selective hA3 antagonist
| Chemical Name: | 1,4-Dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-3,5-pyridinedicarboxylic acid 3-ethyl-5-[(3-nitrophenyl)methyl] ester |
| Purity: | ≥98% (HPLC) |
