Compounds for HSC Proliferation and Renewal: Small Molecules and Peptides
15 results for "Compounds for HSC Proliferation and Renewal Small Molecules and Peptides" in Products
15 results for "Compounds for HSC Proliferation and Renewal Small Molecules and Peptides" in Products
Compounds for HSC Proliferation and Renewal: Small Molecules and Peptides
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% (HPLC) |
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names: | CHIR99021,CT99021 |
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥98% (HPLC) |
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
| Alternate Names: | PGE2 |
| Chemical Name: | (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of p38 MAPK
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity: | ≥98% (HPLC) |
Glutathione (GSH) precursor; neuroprotective
| Chemical Name: | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
PARP-1 inhibitor
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% (HPLC) |
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
| Chemical Name: | (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥95% (HPLC) |
Potent GSK-3 inhibitor; also inhibits cdks
| Alternate Names: | 6BIO |
| Chemical Name: | (2'Z,3'E)-6-Bromoindirubin-3'-oxime |
| Purity: | ≥98% (HPLC) |
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥97% (HPLC) |
Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
| Chemical Name: | 4-[2-[[2-Benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]phenol |
| Purity: | ≥98% (HPLC) |
Dipeptidyl peptidase IV (DPP-IV) inhibitor
| Alternate Names: | Ile-Pro-Ile |
| Chemical Name: | L-Isoleucyl-L-prolyl-L-isoleucine |
| Purity: | ≥98% (HPLC) |
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Chemical Name: | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Purity: | ≥98% (HPLC) |
Potent aryl hydrocarbon receptor (AhR) antagonist
| Chemical Name: | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent FBPase inhibitor; promotes HSC expansion
| Chemical Name: | P-[5-[2-Amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphonic acid |
| Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names: | TEN 010 |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
