gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
217 results for "gp130" in Products
217 results for "gp130" in Products
gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
| Sensitivity: |
0.05 ng/mL (Cell Culture Supernates) 0.08 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | ELISA |
| Assay Range: |
0.125 - 8 ng/mL (Cell Culture Supernates) 0.25 - 16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Simple Plex Human GP130 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Source: | NS0 |
| Accession #: | P40189 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q6PDI9 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40189 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow, CyTOF-ready, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29104 |
| Applications: | ELISA |
Control for use with Human gp130 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28105 |
| Applications: | IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow |
Biotinylated
| Source: | HEK293 |
| Accession #: | AAA59155.1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #125605 |
| Applications: | Neut |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #745314 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: gp130/CD130 Antibody [NBP2-15776]](https://resources.bio-techne.com/images/products/gp130-CD130-Antibody-Western-Blot-NBP2-15776-img0009.jpg "Western Blot: gp130/CD130 Antibody [NBP2-15776]")
Biotinylated
| Source: | CHO |
| Accession #: | AAA59155.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow |