Inositol Lipid Inhibitors: Small Molecules and Peptides
Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.
11 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products
11 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products
Inositol Lipid Inhibitors: Small Molecules and Peptides
Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| Chemical Name: | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥99% (HPLC) |
Non-selective PI 3-kinase inhibitor
| Chemical Name: | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
| Alternate Names: | SL-2052 |
| Chemical Name: | (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione |
| Purity: | ≥98% (HPLC) |
Inositol monophosphatase inhibitor
| Chemical Name: | [1-(4-Hydroxyphenoxy)ethylidene]bisphosphonic acid |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% (HPLC) |
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
| Chemical Name: | 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Inhibitor of IP6K; also inhibits IP3K
| Chemical Name: | N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine |
| Purity: | ≥97% (HPLC) |
Class III PI 3-kinase inhibitor; also inhibits autophagy
| Alternate Names: | 3-MA |
| Chemical Name: | 3-Methyl-3H-purin-6-amine |
| Purity: | ≥99% (HPLC) |
Potent and selective PI 3-kinase β inhibitor
| Chemical Name: | 7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
| Chemical Name: | α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Purity: | ≥98% (HPLC) |
Potent and selective PI 3-Kβ inhibitor
| Chemical Name: | (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid |
| Purity: | ≥98% |
