Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
7 results for "Mcl-1" in Products
7 results for "Mcl-1" in Products
Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #542808 |
| Applications: | WB, IHC, KO |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Mcl-1 Antibody [NB100-56146]](https://resources.bio-techne.com/images/products/MCL1-Antibody-Western-Blot-NB100-56146-img0002.jpg "Western Blot: Mcl-1 Antibody [NB100-56146]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Mcl-1 Antibody (CL1128) [NBP2-52968]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-CL1128-Western-Blot-NBP2-52968-img0005.jpg "Western Blot: Mcl-1 Antibody (CL1128) [NBP2-52968]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, KO |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602901 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8C6 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Mcl-1 Antibody (8C6)BSA Free [NB100-2194]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-8C6D4B1-Western-Blot-NB100-2194-img0008.jpg "Western Blot: Mcl-1 Antibody (8C6)BSA Free [NB100-2194]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Mcl-1 Antibody [NBP1-90006]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-Immunohistochemistry-Paraffin-NBP1-90006-img0003.jpg "Immunohistochemistry-Paraffin: Mcl-1 Antibody [NBP1-90006]")