ABAT Antibody (S08-9E3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19553

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19553-100ul
NBP3-19553-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-9E3

Concentration

0.3 mg/ml

View all ABAT Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human ABAT (Uniprot # P80404)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ABAT Antibody (S08-9E3)

Western Blot: ABAT Antibody (S08-9E3) [NBP3-19553]

Western Blot: ABAT Antibody (S08-9E3) [NBP3-19553]

Western Blot: ABAT Antibody (S08-9E3) [NBP3-19553] - Western blot detection of ABAT in Rat Brain lysates using NBP3-19553 (1:1000 diluted). Predicted band size: 56kDa. Observed band size: 56kDa.

Applications for ABAT Antibody (S08-9E3)

Application
Recommended Usage

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ABAT

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq]

Long Name

4-aminobutyrate aminotransferase, mitochondrial

Alternate Names

EC 2.6.1.19, EC 2.6.1.22, GABA transaminase, GABA-AT, GABA-T, GABAT, L-AIBAT

Gene Symbol

ABAT

Additional ABAT Products

Product Documents for ABAT Antibody (S08-9E3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ABAT Antibody (S08-9E3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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