ABCB11 Antibody (IHC518)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75980

Novus Biologicals, part of Bio-Techne
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NBP2-75980-1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # IHC518

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ABCB11 Antibodies »

Product Summary for ABCB11 Antibody (IHC518)

Immunogen

Recombinant Human BSEP

Localization

Membranous

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ABCB11 Antibody (IHC518)

Immunohistochemistry-Paraffin: ABCB11 Antibody (IHC518) [NBP2-75980]

Immunohistochemistry-Paraffin: ABCB11 Antibody (IHC518) [NBP2-75980]

Immunohistochemistry-Paraffin: ABCB11 Antibody (IHC518) [NBP2-75980] - Staining of ABCB11 Antibody (IHC518) in liver.

Applications for ABCB11 Antibody (IHC518)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:200

Immunohistochemistry-Paraffin

1:100 - 1:200
Application Notes
Visualization of the antigen present in tissue sections is accomplished in a multi-step immunohistochemical staining process, in conjunction with a horseradish peroxidase (HRP) or alkaline phosphatase (AP) linked detection system. Positive control: Liver.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Tris Buffer, pH 7.3 - 7.7, 1% BSA

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ABCB11

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. (provided by RefSeq)

Alternate Names

ABC member 16, MDR/TAP subfamily, ABC16, ATP-binding cassette sub-family B member 11, ATP-binding cassette, sub-family B (MDR/TAP), member 11, bile salt export pump, BSEP, BSEPPFIC2, EC 3.6.3, EC 3.6.3.44, PFIC-2, PGY4, progressive familial intrahepatic cholestasis 2, sister p-glycoprotein, SPGPBRIC2

Gene Symbol

ABCB11

Additional ABCB11 Products

Product Documents for ABCB11 Antibody (IHC518)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ABCB11 Antibody (IHC518)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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