ABCD1 Antibody (9D11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42921

Novus Biologicals, part of Bio-Techne
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NBP3-42921
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 9D11

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ABCD1 Antibodies »

Product Specifications

Immunogen

ATP-binding cassette, sub-family D(ALD), member 1 - (Uniprot# P33897)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ABCD1 Antibody (9D11)

ABCD1 Antibody (9D11)

Immunocytochemistry/ Immunofluorescence: ABCD1 Antibody (9D11) [NBP3-42921] -

Immunocytochemistry/ Immunofluorescence: ABCD1 Antibody (9D11) [NBP3-42921] - Immunofluorescence analysis of Hela cells using (ABCD1 antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.
ABCD1 Antibody (9D11)

Western Blot: ABCD1 Antibody (9D11) [NBP3-42921] -

Western Blot: ABCD1 Antibody (9D11) [NBP3-42921] - HeLa cells were subjected to SDS PAGE followed by western blot with (ABCD1 antibody) at dilution of 1:400

Applications for ABCD1 Antibody (9D11)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20 - 1:200

Western Blot

1:200 - 1:1000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ABCD1

ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCD1 is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. ABCD1 peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in ABCD1 have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Alternate Names

Adrenoleukodystrophy protein, ALDATP-binding cassette sub-family D member 1, ALDPadrenoleukodystrophy, AMNABC42, ATP-binding cassette, sub-family D (ALD), member 1

Gene Symbol

ABCD1

Additional ABCD1 Products

Product Documents for ABCD1 Antibody (9D11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ABCD1 Antibody (9D11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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