ABCD1 Antibody (OTI2C12) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-70150CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-46476

Alexa Fluor 350

NBP2-70150AF350

Alexa Fluor 405

NBP2-70150AF405

Alexa Fluor 488

NBP2-70150AF488

Alexa Fluor 532

NBP2-70150AF532

Alexa Fluor 594

NBP2-70150AF594

Alexa Fluor 647

NBP2-70150AF647

Alexa Fluor 700

NBP2-70150AF700

Alexa Fluor 750

NBP2-70150AF750

Allophycocyanin

NBP2-70150APC

Biotin

NBP2-70150B

DyLight 350

NBP2-70150UV

DyLight 405

NBP2-70150V

DyLight 488

NBP2-70150G

DyLight 550

NBP2-70150R

DyLight 594

NBP2-70150DL594

DyLight 650

NBP2-70150C

DyLight 680

NBP2-70150FR

DyLight 755

NBP2-70150IR

FITC

NBP2-70150F

HRP

NBP2-70150H

Janelia Fluor 525

NBP2-70150JF525

Janelia Fluor 549

NBP2-70150JF549

Janelia Fluor 646

NBP2-70150JF646

Janelia Fluor 669

NBP2-70150JF669

PE

NBP2-70150PE

PerCP

NBP2-70150PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-70150

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Knockout Validated, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG_2A Clone # OTI2C12

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ABCD1 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 508-745 of human ABCD1 (NP_000024) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for ABCD1 Antibody (OTI2C12) [CoraFluor™ 1]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: ABCD1

ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCD1 is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. ABCD1 peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in ABCD1 have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Alternate Names

Adrenoleukodystrophy protein, ALDATP-binding cassette sub-family D member 1, ALDPadrenoleukodystrophy, AMNABC42, ATP-binding cassette, sub-family D (ALD), member 1

Gene Symbol

ABCD1

Additional ABCD1 Products

Product Documents for ABCD1 Antibody (OTI2C12) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ABCD1 Antibody (OTI2C12) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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