ABCE1 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58061
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Mouse (100%), Rat (99%). Backed by our 100% Guarantee.
Applications
Immunocytochemistry/ Immunofluorescence, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: KAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINP
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for ABCE1 Antibody
![Western Blot: ABCE1 Antibody [NBP2-58061]](https://resources.bio-techne.com/images/products/ABCE1-Antibody-Western-Blot-NBP2-58061-img0002.jpg "Western Blot: ABCE1 Antibody [NBP2-58061]")
Western Blot: ABCE1 Antibody [NBP2-58061]
Western Blot: ABCE1 Antibody [NBP2-58061] - Analysis in human cell line RT-4 and human cell line U-251 MG.![Immunocytochemistry/ Immunofluorescence: ABCE1 Antibody [NBP2-58061]](https://resources.bio-techne.com/images/products/ABCE1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58061-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ABCE1 Antibody [NBP2-58061]")
Immunocytochemistry/ Immunofluorescence: ABCE1 Antibody [NBP2-58061]
Immunocytochemistry/Immunofluorescence: ABCE1 Antibody [NBP2-58061] - Staining of human cell line U-251 MG shows localization to cytosol. Antibody staining is shown in green.Applications for ABCE1 Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
0.25-2 ug/ml
Western Blot
0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: ABCE1
ABCE-1 interacts with RNASEL to inhibit its endoribonuclease activity, and antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. ABCE1 is activated by encephalomyocarditis virus (EMCV) and HIV-1, and recently it has been found to be essential for the assembly of immature immunodeficiency virus capsids.
ABCE1 antibodies are useful tools for HIV studies and research on the ATP-binding cassette families.
Alternate Names
2'-5'-oligoadenylate-binding protein, ATP-binding cassette, sub-family E (OABP), member 1, huHP68, OABP, Ribonuclease 4 inhibitor, ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor, RLIABC38, RNase L inhibitor, RNASEL1, RNASELIRNS4IATP-binding cassette sub-family E member 1
Gene Symbol
ABCE1
Additional ABCE1 Products
Product Documents for ABCE1 Antibody
Product Specific Notices for ABCE1 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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