ACCN4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15241

Novus Biologicals, part of Bio-Techne
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NBP2-15241
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rabbit (95%), Rat (96%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ACCN4 Antibodies »

Product Summary for ACCN4 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human ACCN4. The exact sequence is proprietary.

Localization

Membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ACCN4 Antibody

Western Blot: ACCN4 Antibody [NBP2-15241]

Western Blot: ACCN4 Antibody [NBP2-15241]

Western Blot: ACCN4 Antibody [NBP2-15241] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with ACCN4 antibody [N1N3] diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Western Blot: ACCN4 Antibody [NBP2-15241]

Western Blot: ACCN4 Antibody [NBP2-15241]

Western Blot: ACCN4 Antibody [NBP2-15241] - Sample (30 ug of whole cell lysate) A: U87-MG B: MCF-7 7.5% SDS PAGE; antibody diluted at 1:1000.

Applications for ACCN4 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ACCN4

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

Acid-sensing ion channel 4, amiloride-sensitive cation channel 4, pituitaryMGC17248, ASIC4MGC24860, BNAC4amiloride-sensitive cation channel 4, brain sodium channel 4

Gene Symbol

ASIC4

UniProt

Q96FT7 (Human)

Additional ACCN4 Products

Product Documents for ACCN4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ACCN4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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