ACD Antibody (OTI2B1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45475

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2B1

Concentration

1 mg/ml

View all ACD Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ACD(NP_001075955) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

57.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ACD Antibody (OTI2B1)

Western Blot: ACD Antibody (OTI2B1) [NBP2-45475]

Western Blot: ACD Antibody (OTI2B1) [NBP2-45475]

Western Blot: ACD Antibody (OTI2B1) [NBP2-45475] - Analysis of extracts (35ug) from 9 different cell lines (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemistry: ACD Antibody (OTI2B1) [NBP2-45475]

Immunohistochemistry: ACD Antibody (OTI2B1) [NBP2-45475]

Immunohistochemistry: ACD Antibody (OTI2B1) [NBP2-45475] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Western Blot: ACD Antibody (OTI2B1) [NBP2-45475]

Western Blot: ACD Antibody (OTI2B1) [NBP2-45475]

Western Blot: ACD Antibody (OTI2B1) [NBP2-45475] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACD.
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Applications for ACD Antibody (OTI2B1)

Application
Recommended Usage

Immunohistochemistry

1:500

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ACD

ACD encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Alternate Names

adrenocortical dysplasia homolog (mouse), Pip1, PIP1Tint1, POT1 and TIN2 organizing protein, POT1 and TIN2-interacting protein, Ptop, PTOPTpp1, TIN2 interacting protein 1, TINT1adrenocortical dysplasia protein homolog, TPP1

Gene Symbol

ACD

Additional ACD Products

Product Documents for ACD Antibody (OTI2B1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ACD Antibody (OTI2B1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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