Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13324

Novus Biologicals, part of Bio-Techne
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NBP3-13324
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Porcine (100%), Rhesus Macaque (100%), Sheep (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Acetyl-CoA Carboxylase alpha/ACACA Antibodies »

Product Summary for Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Ser79 of rat Acetyl-CoA Carboxylase alpha/ACACA. The exact sequence is proprietary.

Modification

p Ser 79

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with Acetyl-CoA Carboxylase alpha/ACACA (phospho Ser79) antibody (NBP3-13324) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324] - Untreated (-) and treated (+) 293T whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with Acetyl-CoA Carboxylase alpha/ACACA (phospho Ser79) antibody (NBP3-13324) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324]

Western Blot: Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody [NBP3-13324] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with Acetyl-CoA Carboxylase alpha/ACACA (phospho Ser79) antibody (NBP3-13324) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
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Applications for Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Acetyl-CoA Carboxylase alpha/ACACA

Acetyl-CoA carboxylase 1 (ACC1) is a biotin dependent lipogenic enzyme that is highly expressed during adipogenesis. ACC1 catalyzes acetyl-CoA carboxylation, producing malonyl-CoA, a metabolite involved in energy homeostasis regulation. Malonyl-CoA is a two carbon donor in the synthesis of long-chain fatty acids and the elongation of fatty acids found in the cystol (1). ACC1 is regulated short-term by citrate, CoA, and palmitoyl-CoA through allosteric interactions. Nutrients and hormones can be both short-term (inducing reversible phosphorylations by such as AMPK) and long-term (transcription level regulation) regulators of ACC1 (2). Highly expressed in lipogenic tissues, ACC1 is found in liver, adipose, and lactating mammary gland (3). ACC1 has been implicated as a target in the development of anti-obesity drugs (4).

Long Name

Acetyl-Coenzyme A Carboxylase alpha

Alternate Names

ACACA, ACC1, ACCA, AcetylCoA Carboxylase alpha

Gene Symbol

ACACA

Additional Acetyl-CoA Carboxylase alpha/ACACA Products

Product Documents for Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Acetyl-CoA Carboxylase alpha/ACACA [p Ser79] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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