Acetyl-CoA Carboxylase Antibody (SR1412)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22652

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22652-100ul
NBP3-22652-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1412

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Acetyl-CoA Carboxylase Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Acetyl-CoA Carboxylase (Uniprot #: Q13085, O00763)

Specificity

Detects endogenous levels of total Acetyl-CoA Carboxylase

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

265 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Acetyl-CoA Carboxylase Antibody (SR1412)

Immunohistochemistry: Acetyl-CoA Carboxylase Antibody (SR1412) [NBP3-22652] -

Immunohistochemistry: Acetyl-CoA Carboxylase Antibody (SR1412) [NBP3-22652] - Immunohistochemical analysis of paraffin-embedded human kidney, using NBP3-22652.

Applications for Acetyl-CoA Carboxylase Antibody (SR1412)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Acetyl-CoA Carboxylase

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternate Names

ACAC, Acac1, ACACAD, ACC, ACC1, ACCA, ACC-alpha, ACCalphaACACalpha, acetyl-CoA carboxylase 1, acetyl-Coenzyme A carboxylase alpha, hACC1

Gene Symbol

ACACA

Additional Acetyl-CoA Carboxylase Products

Product Documents for Acetyl-CoA Carboxylase Antibody (SR1412)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Acetyl-CoA Carboxylase Antibody (SR1412)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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