Acetylcholinesterase/ACHE Antibody (12B4) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-05139JF549

Novus Biologicals, part of Bio-Techne
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NBP1-05139
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 12B4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Acetylcholinesterase/ACHE Antibodies »

Product Summary for Acetylcholinesterase/ACHE Antibody (12B4) [Janelia Fluor® 549]

Immunogen

Brain acetylcholinesterase, human, purified and detergent solubilized (1).

Reactivity Notes

Does not react with Human.

Specificity

Specificity for human acetylcholinesterase. No cross-reaction is seen with human BtChE, or with AChE from flounder or Torpedo marmorata.

Marker

Early Neuronal Development Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Acetylcholinesterase/ACHE Antibody (12B4) [Janelia Fluor® 549]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Acetylcholinesterase/ACHE

Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft.

Alternate Names

ACHE, ARACHE, N-ACHE

Gene Symbol

ACHE

Additional Acetylcholinesterase/ACHE Products

Product Documents for Acetylcholinesterase/ACHE Antibody (12B4) [Janelia Fluor® 549]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Acetylcholinesterase/ACHE Antibody (12B4) [Janelia Fluor® 549]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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