ACF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42352

Novus Biologicals, part of Bio-Techne
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NBP3-42352
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.75 mg/ml

View all ACF Antibodies »

Product Specifications

Immunogen

Immunogen sequence: Gly389-Arg587 (Uniprot#: Q9NQ94)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ACF Antibody

ACF Antibody

Western Blot: ACF Antibody [NBP3-42352] -

Western Blot: ACF Antibody [NBP3-42352] - Sample: Recombinant ACF, Human.
ACF Antibody

Western Blot: ACF Antibody [NBP3-42352] -

Western Blot: ACF Antibody [NBP3-42352] - Sample: Lane1: Porcine Liver Tissue; Lane2: Human Hela Cells; Lane3: Human Jurkat Cells; Lane4: Human 293T Cells.
ACF Antibody

Immunohistochemistry-Paraffin: ACF Antibody [NBP3-42352] -

Immunohistochemistry-Paraffin: ACF Antibody [NBP3-42352] - DAB staining on IHC-P; Samples: Human Stomach Tissue; Primary Ab: 10ug/ml NBP3-42352

Applications for ACF Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

0.75 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ACF

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined. [provided by RefSeq]

Alternate Names

ACF65, ACFASPACF64, apo-B RNA editing protein, APOBEC1 complementation factor, apobec-1 complementation factor (ACF) (ASP), APOBEC-1 stimulating protein, APOBEC1CF, APOBEC1-stimulating protein, MGC163391

Gene Symbol

A1CF

Additional ACF Products

Product Documents for ACF Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ACF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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