Acinus Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98082

Novus Biologicals, part of Bio-Techne
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NBP2-98082-100ul
NBP2-98082-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Acinus Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human Acinus fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Acinus Antibody

Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082]

Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082]

Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082] - Immunochemical staining of human Acinus in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082]

Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082]

Immunohistochemistry-Paraffin: Acinus Antibody [NBP2-98082] - Immunochemical staining of human Acinus in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Applications for Acinus Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Acinus

Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), Acinus S (583 amino acids) and Acinus S; (614 amino acids).

Alternate Names

ACINUS, ACN, apoptotic chromatin condensation inducer 1, apoptotic chromatin condensation inducer in the nucleus, fSAP152, functional spliceosome-associated protein 152, KIAA0670DKFZp667N107

Gene Symbol

ACIN1

Additional Acinus Products

Product Documents for Acinus Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Acinus Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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