Activin B/Inhibin beta B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00003625-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Proximity Ligation Assay, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Activin B Antibodies »

Product Specifications

Immunogen

INHBB (AAH30029.1, 1 a.a. - 407 a.a.) full-length human protein. MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAQPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTSYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA

Specificity

INHBB,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Activin B/Inhibin beta B Antibody

Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P] - Analysis of INHBB expression in mouse brain.
Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Western Blot: Activin B/Inhibin beta B Antibody [H00003625-D01P] - Analysis of INHBB expression in transfected 293T cell line by INHBB polyclonal antibody.Lane 1: INHBB transfected lysate(45.20 KDa).Lane 2: Non-transfected lysate.
Proximity Ligation Assay: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Proximity Ligation Assay: Activin B/Inhibin beta B Antibody [H00003625-D01P]

Proximity Ligation Assay: Activin B/Inhibin beta B Antibody [H00003625-D01P] - Analysis of protein-protein interactions between INHBB and ACVR1C. HeLa cells were stained with anti-INHBB rabbit purified polyclonal 1:1200 and anti-ACVR1C mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Applications for Activin B/Inhibin beta B Antibody

Application
Recommended Usage

Proximity Ligation Assay

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for ELISA and WB.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Activin B

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]

Long Name

Inhibin Subunit Beta B

Alternate Names

activin AB beta polypeptide, Activin Beta B, Activin beta-B chain, INHBB, Inhibin Beta B, inhibin beta B chain, Inhibin Subunit Beta B, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2

Entrez Gene IDs

3625 (Human)

Gene Symbol

INHBB

UniProt

AAH30029.1 (Human)

Additional Activin B Products

Product Documents for Activin B/Inhibin beta B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Activin B/Inhibin beta B Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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