Activin B/Inhibin beta B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16966

Novus Biologicals, part of Bio-Techne
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NBP2-16966
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Zebrafish

Predicted:

Bovine (100%), Chicken (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Activin B Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Activin B/Inhibin beta B. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Activin B/Inhibin beta B Antibody

Western Blot: Activin B/Inhibin beta B Antibody [NBP2-16966]

Western Blot: Activin B/Inhibin beta B Antibody [NBP2-16966]

Western Blot: Activin B/Inhibin beta B Antibody [NBP2-16966] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Inhibin beta B antibody [C3], C-term diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Immunohistochemistry-Frozen: Activin B/Inhibin beta B Antibody [NBP2-16966]

Immunohistochemistry-Frozen: Activin B/Inhibin beta B Antibody [NBP2-16966]

Immunohistochemistry-Frozen: Activin B/Inhibin beta B Antibody [NBP2-16966] - Analysis of zebrafish eye frozen section with at a 1:750 dilution.
Immunohistochemistry-Paraffin: Activin B/Inhibin beta B Antibody [NBP2-16966]

Immunohistochemistry-Paraffin: Activin B/Inhibin beta B Antibody [NBP2-16966]

Immunohistochemistry-Paraffin: Activin B/Inhibin beta B Antibody [NBP2-16966] - Human normal kidney. Inhibin beta B antibody [C3], C-term diluted at 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Applications for Activin B/Inhibin beta B Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Frozen

Assay dependent

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Activin B

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]

Long Name

Inhibin Subunit Beta B

Alternate Names

activin AB beta polypeptide, Activin Beta B, Activin beta-B chain, INHBB, Inhibin Beta B, inhibin beta B chain, Inhibin Subunit Beta B, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2

Gene Symbol

INHBB

UniProt

P09529

Additional Activin B Products

Product Documents for Activin B/Inhibin beta B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Activin B/Inhibin beta B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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